Abortion pill side effects vs. complications—how to tell the difference

AVA Care in Harrisonburg, Virginia



If you’re considering the abortion pill, it’s important to understand what your body may experience as a result. While some symptoms are expected, others could signal a more serious issue. Knowing the difference between common side effects and potential complications can help you make informed decisions and seek appropriate medical care when needed.

What is the abortion pill?

The abortion pill typically involves two medications; mifepristone and misoprostol, taken to end an early pregnancy (FDA-approved up to 10-weeks(2)). These medications work together to block hormones and cause the uterus to contract and expel the pregnancy.

Common side effects 

Many women experience side effects after taking the abortion pill. These are expected as your body responds to the medication (1):

• Cramping (often stronger than a typical period)
• Vaginal bleeding (can be heavy with clots)
• Nausea or vomiting
• Diarrhea
• Fever or chills (usually within the first 24 hours)
• Fatigue



These side effects can vary in intensity. Bleeding may continue for 1–2 weeks or longer in some cases.

Possible complications (when to be concerned)

While less common, complications can occur and may require medical attention. Watch for these warning signs (1):

• Excessive bleeding (soaking 2 or more pads per hour for 2 consecutive hours)
• Severe abdominal pain that doesn’t improve with medication
• Fever lasting more than 24 hours or starting days after taking the pill
• Foul-smelling vaginal discharge
• No bleeding at all after taking misoprostol
• Signs of ongoing pregnancy (like persistent nausea, breast tenderness, or a positive pregnancy test after 4-6 weeks)

These symptoms could indicate infection, an incomplete abortion (3), or an ectopic pregnancy (4), all of which require prompt medical evaluation.

What if you change your mind?

Support is available

At AVA Care in Harrisonburg, Virginia, you can receive accurate information, pregnancy confirmation, and support in a confidential and compassionate environment. If you have questions about the abortion pill or want to explore all your options, AVA Care is here for you. AVA Care also offers after abortion assessments 4-6 weeks following an abortion, which includes a medical assessment and a safe space to process your abortion experience. 

Every woman’s experience is different. While some symptoms are expected, you should never ignore signs that something may be wrong. Trust your instincts and seek care if you’re concerned. 



You deserve clear answers, compassionate support, and care you can trust. AVA Care of Harrisonburg is here for you. 

Citations: 

1. Mayoclinic.org 
2. FDA Approved up to 10 weeks
3. Incomplete Abortion
4. Ectopic Pregnancy
5. Abortion Pill Reversal